In this phase the individual steps of the laboratory model that are divided into separate modules are integrated to the MAZER functional prototype. Different model assays will be transferred to MAZER and adapted and optimized on the MAZER card. In this way all process steps are integrated on a miniaturized compact diagnostics system. In addition a special sample preparation module, that can be connected to the universal MAZER card will be developed and tested.
In this way all process steps are integrated on a miniaturized compact diagnostics system. In addition a special sample preparation module, that can be connected to the universal MAZER card will be developed and tested.
In the validation phase, complex tests will be transferred to the MAZER. Furthermore clinical protocols will be developed for the validation of the system based on clinical samples. The advanced prototype contains all electrical and mechanical components. Detection electronics and necessary computer hardware with a display will have already been integrated. It consists of an integrated test MAZER card and a hand-held, which will run existing genomic and proteonomic assays which have been transferred from other diagnostic platforms.
The BMBF-funded MinoLab project for the development of the MAZER prototype was completed in 2014, which unites the separate single processes in a fully integrated system. The MAZER platform is ready for the transfer of complex assays that require clinical validation, before the platform can be introduced to market.
